Wild Sweet Orange was an American indie rock band from Homewood, Alabama. In early 2008 their song "Land of No Return" was featured on Grey's Anatomy. The band performed the song "Ten Dead Dogs" live on the Late Night with David Letterman on June 23, 2008. Their first full LP, We Have Cause to Be Uneasy, was released on July 29, 2008. Wild Sweet Orange has opened for bands such as Counting Crows, Guster, Augustana, and Gringo Star.

On September 7, 2010, the band announced on their Facebook page that they were calling it quits.